Another mode of action for the antiinammatory drugs is by inhibiting the generation of reactive oxygen species or through their scavenging. It has been demonstrated in different studies that there exists a strong bond between the antiinammatory and the antioxidant properties. Yet, the consumption of antiinammatory drugs over a prolonged period of time is associated with a great amount of secondary effects, thereby, increasing the costs in healthcare.Therefore, it should be of great interest to search novel natural alternative sources of drugs for treating chronic inammatory pathologies.A signicant role in human health is being played by natural products with respect to preventing and treating inammatory conditions. One of the most important aspects of complementary medicines is herbal medication, and the process of inammation has several mechanisms and number of treatment methods consequently.The aqueous methanolic leaf extract of strychnine tree. Moreover, the analysis of phenolic compounds through high performance liquid chromatography revealed that the leaf extracts comprised of active phenolic compounds like myricetin, quercetin, rutin, chlorogenic acid, resveratrol, catechin and ferulic acid which were considered responsible for the antiinammatory properties. Inammation and pain have been reported to be responsible for various pathological conditions.For mankind, roots as well as herbaceous parts of leguminous crops have not been utilized generally because these have been conventionally regarded as waste substances.Despites not regarded as consumable, such parts of leguminous crops have a complex chemical composition possessing remarkable biological potentials.Therefore, these results were indicative of a strong capability of waste legume material as a potential source to isolate bioactive antiinammatory as well as antioxidant compounds to be utilized as therapeutic as well as dietary additives in the food as well as pharmaceutical industry. Hence, it was concluded that this extract exerted in vitro as well as in vivo antiinammatory potential through the inhibition of PDK kinase action, which in turn blocked the signal to its downstream transcription factor, NF. cells treated with lipopolysaccharide.Cymbopogon citratus is among one of the known aromatic plants being used throughout world in the conventional system of medicine for curing inammation associated conditions.edema separately. In addition to this, modulation of the expression of proinammatory chemokines and cytokines was S.Therefore, these results were suggestive of the antiinammatory property of these fruits due to the modulation of neutrophil migration, retardation of chemokines, cytokines, and adhesion molecules.Hence, these fruits can be used in the production of food additives as well as functional foods. Moreover, the antiinammatory capacity of its extract as well as the isolated pure compounds could be compared to that of diclofenac sodium. Further, fractionation of this extract was carried and it was found that its dichloromethane fraction was the most potential fraction in vitro, suppressing the synthesis of prostaglandin E, nitric oxide, tumor necrosis factor, monocyte chemotactic protein, interleukin b and IL.Moreover, this fraction signicantly inhibited penetration inside tissue. Among the crucial health issues are pain and inammation that have been usually cured through conventional treatments chiey through the help of medicinal crops.Moreover, the extract also remarkably decreased the amount of leukocyte having same activities to diclofenac in the rats that were treated with carrageenan.