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Inhibitor Myostatin

Oncogenic KRAS and BRAF differentially regulate hypoxiainducible factoralpha and alpha in colon Nalmefene hydrochloride cancer.Regulation of tumor angiogenesis by pinduced degradation of hypoxiainducible factor alpha.Hypoxia and radiation response in human tumors.Oxygen status of malignant tumors: pathogenesis of hypoxia and significance for tumor therapy.Hypoxiainducible factordependent regulation of the multidrug resistance gene.Tumorderived vascular endothelial growth factor upregulates angiopoietin in host endothelium and destabilizes host vasculature, supporting angiogenesis in ovarian cancer.Hypoxiainduced upregulation of angiopoietin in colorectal cancer.Stem cell factorckit signaling promotes the survival, migration, and capillary tube formation of human umbilical vein endothelial cells.Progenitor cell trafficking is regulated by hypoxic gradients through HIF induction of SDF.Inhibition of vasculogenesis, but not angiogenesis, prevents the recurrence of glioblastoma after irradiation in mice.Hypoxiainducible factor alpha regulates macrophage function in mouse models of acute and tumor inflammation.Combination angiostatic therapy completely inhibits ocular and tumor angiogenesis.ME inhibits tumor growth and angiogenesis by disrupting microtubules and dysregulating HIF.methoxyestradiol inhibits hypoxiainducible factor alpha, tumor growth, and angiogenesis and augments paclitaxel efficacy in head and neck squamous cell carcinoma.Part: clinical evaluation and noninvasive diagnosis.Transcriptional regulation of vascular endothelial cell responses to hypoxia by HIF.Increased endogenous angiogenic response and hypoxiainducible factoralpha in human critical limb ischemia.Effects of aging and hypoxiainducible factor activity on angiogenic cell mobilization and recovery of perfusion after limb ischemia.Role of ischemia and of hypoxiainducible genes in arteriogenesis after femoral artery occlusion in the rabbit.Mouse model of angiogenesis.Murine model of hindlimb ischemia.Hemodynamic and metabolic diffuse optical monitoring in a mouse model of hindlimb ischemia.Evaluation of postnatal arteriogenesis and angiogenesis in a mouse model of hindlimb ischemia.Contribution of arteriogenesis and angiogenesis to postocclusive hindlimb perfusion in mice.Arteriogenesis versus angiogenesis: similarities and differences.Cellular dysfunction in the diabetic fibroblast: impairment in migration, vascular endothelial growth factor production, and response to hypoxia.Hyperglycemia regulates hypoxiainducible factoralpha protein stability and function.Adult hematopoietic stem cells provide functional hemangioblast activity during retinal neovascularization.Peripheral blood endothelial progenitor cells are derived from monocytemacrophages and secrete angiogenic growth factors.Expression of vascular endothelial growth factor receptor in bone marrowderived mesenchymal cells is dependent on hypoxiainducible factor. Thyroid hormone mediated changes in gene expression can be initiated by cytosolic action of the thyroid hormone receptor beta through the phosphatidylinositol kinase pathway.Endothelial colony forming cells and mesenchymal stem cells are enriched at different gestational ages in human umbilical cord blood.Regulation of the chemokine receptor CXCR by hypoxia.Age decreases endothelial progenitor cell recruitment through decreases in hypoxiainducible factor alpha stabilization during ischemia.Interindividual heterogeneity in the hypoxic regulation of VEGF: significance for the development of the coronary artery collateral circulation.Hypoxiainducible factor alpha polymorphism and coronary collaterals in patients with ischemic heart Pramipexole disease.Polymorphisms in hypoxia inducible factor and the initial clinical presentation of coronary disease.Failure to prolyl hydroxylate hypoxiainducible factor alpha phenocopies VHL inactivation in vivo.Circulating endothelial progenitor cells are reduced in peripheral vascular complications of type diabetes mellitus.A hypoxic inducible factor alpha hybrid enhances collateral development and reduces vascular leakage in diabetic rats.Oxygen tension regulates the expression of a group of procollagen hydroxylases.Interaction of hydroxylated collagen IV with the von hippellindau tumor suppressor.Ranibizumab versus verteporfin for neovascular agerelated macular degeneration.

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